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Comments from US Federal Reserve Governor Lael Brainard spooked investors about potential aggressive policy actions by the US central bank to control inflation. Technology shares fell sharply, led lower by Apple (-1.9%) and Amazon (-2.6%). But shares of Twitter (+2%) extended gains on plans to offer Tesla CEO and entrepreneur Elon Musk a seat on its board of directors. At the close of trade, the Dow Jones index fell by 281 points or 0.8%. The S&P 500 index slid 1.3% and the Nasdaq index shed 328 points or 2.3%.