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Sky News host Paul Murray says US Democratic candidate Bernie Sanders is on to his "last roll of the dice" to have any chance of facing Donald Trump at the upcoming presidential election.

Former US Vice President Joe Biden has experienced a string of strong results against Mr Sanders in recent primary elections.

Mr Biden won the majority of votes in Florida, Illinois and Arizona which placed him far ahead of Democrat rival Bernie Sanders.

"It will be Joe Biden against Donald Trump," Mr Murray said.

Image: AP